2,3-benzodiazepine derivatives and their use as AMPA-receptor inhibitors
US6200970A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 5, 1998 |
| Grant date | Mar 13, 2001 |
| Priority date | — |
| Expiry date | Nov 5, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound of formula I ##STR1## in which PA1 X means hydrogen or halogen, PA1 Y means --NR.sup.3 -- or --N.dbd., PA1 R.sup.1 and R.sup.2 are the same or different and mean hydrogen, C.sub.1 -C.sub.6 alkyl, nitro, halogen, the group --NR.sup.8 R.sup.9, --O--C.sub.1-4 alkyl, --CF.sub.3, OH or C.sub.1-6 alkanoyloxy, PA1 R.sup.3 means hydrogen, the group --CO--R.sup.10, C.sub.1-6 alkyl or C.sub.3-7 cycloalkyl, PA1 R.sup.4 means optionally substituted C.sub.1 -C.sub.6 alkyl, PA1 R.sup.5 means hydrogen or PA1 R.sup.4 and R.sup.5 together mean oxygen, PA1 R.sup.6 means C.sub.1-4 alkyl, PA1 R.sup.8 and R.sup.9 are the same or different and mean hydrogen, C.sub.1 -C.sub.6 alkyl or --CO--C.sub.1-6 alkyl, PA1 R.sup.10 means hydrogen, optionally substituted C.sub.1 -C.sub.6 alkyl, optionally substituted C.sub.6-10 aryl, the group --NR.sup.11 R.sup.12, --O--C.sub.1-6 alkyl, C.sub.3-7 cycloalkyl, C.sub.2-6 alkenyl or --O--C.sub.3-7 cycloalkyl, PA1 R.sup.11 and R.sup.12 are the same or different and mean hydrogen, optionally substituted C.sub.1 -C.sub.6 alkyl or optionally substituted C.sub.6-10 aryl and PA1 --C.sub.... C.sub.... means a double bond or single bonds or an isomer or physiologicall…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.