Pentanoic acid derivatives
US6201021A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 23, 1996 |
| Grant date | Mar 13, 2001 |
| Priority date | — |
| Expiry date | Jul 23, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/185
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Formula (I) compounds: ##STR1## wherein R.sup.1 is alkyl substituted by fluorine(s); R.sup.2 is hydroxy, alkoxy, alkoxy substituted by phenyl, NR.sup.3 R.sup.4, in which R.sup.3, R.sup.4 is (i) hydrogen, (ii) alkyl, (iii) phenyl, (iv) phenyl substituted by alkoxy or carboxyl, (v) heterocyclic ring containing nitrogen atom, (vi) alkyl substituted by phenyl, phenyl subsituted by alkoxy or carboxyl, heterocyclic ring containing nitrogen atom, (vii) the nitrogen bonded to R.sup.3 and R.sup.4, taken together is a saturated heterocyclic ring or amino acid residue; and non-toxic salts and acid addition salts thereof. Also, Formula (X) compounds: ##STR2## wherein n is 0 or 1, R.sup.11 is hydrogen and chlorine, R.sup.5 is R.sup.7 --CH.sub.2 -- or R.sup.8, or R.sup.5 and R.sup.11, taken together is alkylidene; R.sup.6 is hydroxy, alkoxy, alkoxy substituted by phenyl, NR.sup.9 R.sup.10, in which R.sup.9, R.sup.10 is (i) hydrogen, (ii) alkyl, (iii) phenyl, (iv) phenyl substituted by alkoxy or carboxyl, (v) heterocyclic ring containing nitrogen atom, (vi) alkyl substituted by phenyl, phenyl-substituted by alkoxy or carboxyl, heterocyclic ring containing nitrogen atom, (vii) the nitrogen bonded …
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.