Substituted .beta. diketones and their use
US6201027A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 1, 1999 |
| Grant date | Mar 13, 2001 |
| Priority date | — |
| Expiry date | Jul 1, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P11/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the compounds of formula I: ##STR1## wherein one of X.sub.1 and X.sub.2 is MeSO.sub.2 and the other one is hydrogen or halogen and X.sub.3 is hydrogen or halogen. These compounds have been found to be useful in the prevention and the treatment of respiratory diseases, especially asthma, ARDS (Acute Respiratory Distress Syndrome), COPD (chronic obstructive pulmonary diseases), allergic rhinitis and related inflammatory conditions. More specifically, the invention relates to the use of said compound in the prevention and the treatment of asthma in steroid-resistant patients. The invention also relates to pharmaceutical formulations used in the treatment of said diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.