Process for the resolution of esters of arylalkylcarboxylic acids
US6201147A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 21, 1999 |
| Grant date | Mar 13, 2001 |
| Priority date | — |
| Expiry date | Sep 21, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P41/003
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a process for the resolution of esters of arylalkylcarboxylic acids of the general formula ##STR1## which comprises reacting compounds of the general formula I with an alcohol of the general formula R.sup.6 --OH in the presence of a lipase or esterase to give compounds of the general formulae Ia and II ##STR2## at least one of the compounds of the formulae Ia and II being present in an enantiomeric excess and the substituents and variables in the formulae I, Ia and II are as defined in the specification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.