Patent · US Expired

Medical device for delivering a therapeutic substance and method therefor

US6203536A · kind A · utility

76Cited by
45References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 17, 1997
Grant dateMar 20, 2001
Priority date
Expiry dateJun 17, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61L33/0011
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

A device useful for localized delivery of a therapeutic material is provided. The device includes a structure including a porous material; and a water-insoluble salt of a therapeutic material dispersed in the porous material. The water-insoluble salt is formed by contacting an aqueous solution of a therapeutic salt with a heavy metal water-soluble salt dispersed throughout a substantial portion of the porous material. The heavy metal water-soluble salt can be dispersed in the porous material so that the device can be sterilized and the therapeutic material can be loaded in the device in situ, for example, just prior to use. The therapeutic material is preferably a heparin or heparin derivative or analog which renders the material antithrombotic as an implantable or invasive device.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.