Patent · US Expired

Methods of preparing compositions comprising chemicals capable of transcriptional modulation

US6203976A · kind A · utility

14Cited by
23References
26Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 7, 1994
Grant dateMar 20, 2001
Priority date
Expiry dateJun 7, 2014

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides a method of transcriptionally modulating the expression of a gene encoding a protein of interest, the expression of which gene is associated with the production in cell culture of a protein encoded by the gene, which comprises contacting a cell, which is capable of expressing the gene, with an amount of a molecule effective to transcriptionally modulate expression of the gene and thereby affect the level of the protein encoded by the gene which is expressed by the cell in culture, which molecule (a) does not naturally occur in the cell and (b) directly transcriptionally modulates expression of the gene.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.