Patent · US Expired

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization

US6203977A · kind A · utility

18Cited by

15References

32Claims

0Family size

Assignee

Yale University · US

Inventors

David C. Ward · Guilford, US
Peter Lichter · Heidelberg, DE
Thomas Cremer · Heidelberg, DE
Laura Manuelidis · New Haven, US
Thomas Ried · Bethesda, US
Antonio Baldini · London, GB

Key dates

Filing date	Sep 26, 1994
Grant date	Mar 20, 2001
Priority date	—
Expiry date	Sep 26, 2014

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/6841
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

This disclosure relates to a method of specifically decorating selected mammalian chromosomes and of detecting, identifying and and/or quantitating selected individual chromosomes, by means of chromosomal in situ suppression (CISS) hybridization. The method is useful in analyzing cells for the occurrence of chromosomes, chromosome fragments or chromosome aberrations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.