Patent · US Expired

CCR5 RNA transcription based amplification assay

US6204024A · kind A · utility

0Cited by
15References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 12, 1997
Grant dateMar 20, 2001
Priority date—
Expiry dateSep 12, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/703
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A method and a test kit for genotyping the CCR5 chemokine receptor. CCR5 transcript DNA is amplified using transcription based amplification. The amplification product is detected through the hybridization of appropriately labeled oligonucleotide wild type and mutant probes. In a liquid hybridization based ECL analysis, the mutant probe is a 16mer having the sequence 5'TCCATACATTAAAGAT3' [SEQ ID NO:9]. The method and kit can be used to predict.

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