.alpha.-amlase mutants

US6204232A · kind A · utility

Assignee

• Novo Nordisk A/S · DK

Inventors

• Torben Vedel Borchert · Nørresundby, DK
• Allan Svendsen · Paseo Los Muchachos, DK
• Carsten Andersen · Frederikssund, DK
• Bjarne R.o slashed.nfeldt Nielsen · Avenue Madeleine, DK
• Torben Lauesgaard Nissen · Summit, US
• S.o slashed.ren Kj.ae butted.rulff

Key dates

• Filing date: Oct 30, 1998
• Grant date: Mar 20, 2001
• Expiry date: Oct 30, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y302/01001
• WIPO field: Basic materials chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to a variant of a parent Termamyl-like .alpha.-amylase, which exhibits an alteration in at least one of the following properties relative to said parent .alpha.-amylase: i) improved pH stability at a pH from 8 to 10.5; and/or ii) improved Ca.sup.2+ stability at pH 8 to 10.5, and/or iii) increased specific activity at temperatures from 10 to 60.degree. C.