Patent · US Expired

Method of peptide synthesis

US6204361A · kind A · utility

32Cited by
3References
98Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 25, 1998
Grant dateMar 20, 2001
Priority date
Expiry dateNov 25, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K14/001
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates to a process for forming an N-.alpha.-amino protected amino acid fluoride in situ by reacting an N-.alpha.-amino protected amino acid with an ionic fluoride salt in the presence of a peptide coupling agent. It is also directed to the use of the amino acid fluoride thus formed in peptide synthesis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.