Synthesis of epothilones, intermediates thereto and analogues thereof
US6204388A · kind A · utility
73Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 24, 1999 |
| Grant date | Mar 20, 2001 |
| Priority date | — |
| Expiry date | Feb 24, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/1892
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype. Also provided are intermediates useful for preparing said epothilones.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.