Sentinel node identification using non-isotope means
US6205352A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Nov 18, 1998 |
| Grant date | Mar 20, 2001 |
| Priority date | — |
| Expiry date | Nov 18, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/222
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for identifying a sentinel node is provided. The method includes injecting tumor-bearing tissue with a marking composition, radiating marking-agent-targeting energy into suspect tissues potentially harboring the sentinel node, and detecting a lymph node within the suspect tissues first infiltrated by the marking agent. The method is conducted without detecting radioactivity, and thus avoids the health and environmental problems posed by methods based on detecting radiolabels. Moreover, the method obviates the need for surgical dissection to initially detect potential sentinel nodes. Also provided are systems for performing the method and compositions for use in the method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.