Devices and methods for applying a mixture of two or more liquid components to form a biomaterial
US6206905A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 21, 1999 |
| Grant date | Mar 27, 2001 |
| Priority date | — |
| Expiry date | Jul 21, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2017/00495
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Novel methods and devices which provide enhanced mixing and application of two liquid components to form a biomaterial with minimized aerosols is achieved using air flow rates below about 1.25 liters/minute in combination with a ratio of air flow to total liquid flow of from about 150:1 up to about 1500:1. Preferably the air flow is below about 1 liter/minute and the ratio of air flow to total liquid flow is from about 200:1 to about 1200:1. The parameters are ideally suited for the spray application of components which form a surgical sealant, e.g., a fibrin sealant. Also a part of the present invention are novel application methods for biomaterial, e.g., surgical sealant, components at liquid flows below 1.9 ml/minute, novel methods involving the mixing of such components on the exit surface of a spray tip or nozzle, novel spray tips and biomaterial applicators and methods for making such applicators.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.