Methods of treatment using antagonists of cytokine synthesis inhibitory factor
US6207154A · kind A · utility
2Cited by
1References
9Claims
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Key dates
| Filing date | Jun 6, 1995 |
| Grant date | Mar 27, 2001 |
| Priority date | — |
| Expiry date | Jun 6, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/141
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Mammalian genes and proteins, designated cytokine synthesis inhibitory factors (CSIFs, now known as Interleukin-10 (IL-10)), are provided which are capable of inhibiting the synthesis of cytokines associated with delayed type hypersensitivity responses, and which, together with antagonists, are useful in treating diseases associated with cytokine imbalances, such as leishmaniasis and other parasitic infections, and certain immune disorders including MHC associated autoimmune diseases caused by excessive production of interferon-.sub..gamma..
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