Therapeutic nanospheres
US6207195A · kind A · utility
43Cited by
0References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 11, 1998 |
| Grant date | Mar 27, 2001 |
| Priority date | — |
| Expiry date | Jun 11, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/923
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
4-Phenylbutyrate exerts many beneficial biological effects. It appears to induce the transcription of certain promoters, as well as having a remedial effect on proteins which are aberrantly localized within the cell. In addition, it appears to cause cells to developmentally differentiate. The present invention provides nanosphere formulations of 4-phenylbutyrate and other drugs which remediate defective protein localization intracellularly. These formulations permit lower concentrations of drugs to be administered, providing both cost and safety benefits.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.