Recombinant AAV vector-based transduction system and use of same

US6207453A · kind A · utility

Assignee

• Medi&Gene Inc. · DE

Inventors

• Gerd Maass · Sindelsdorf, DE
• Christoph Bogedain · Munich, DE
• Michael Hallek · Cologne, DE
• Clemens Wendtner · Munich, DE
• Doris Michl · Munich, DE

Key dates

• Filing date: May 5, 1999
• Grant date: Mar 27, 2001
• Expiry date: May 5, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2750/14143
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a transduction system, comprising (a) a rep-negative AAV vector containing a foreign DNA and (b) a product providing an AAV Rep protein. The invention also relates to the use of the transduction system.