Cycloalkano-pyridines

US6207671A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Gunter Schmidt · Houghton, US
• Arndt Brandes · Wuppertal, DE
• Rolf Angerbauer · Wuppertal, DE
• Michael Logers · Wuppertal, DE
• Matthias Muller-Gliemann · Haan, DE
• Carsten Schmeck · Wuppertal, DE
• Klaus-Dieter Bremm · Recklinghausen, DE
• Hilmar Bischoff · Wuppertal, DE
• Delf Schmidt · Wuppertal, DE
• Joachim Schuhmacher · Wuppertal, DE
• Henry Giera · Wittlich, DE
• Holger Paulsen · Wuppertal, DE
• Paul Naab · Bad Reichenhall, DE
• Michael Conrad · Wuppertal, DE
• Jurgen Stoltefuss · Haan, DE

Key dates

• Filing date: Mar 8, 2000
• Grant date: Mar 27, 2001
• Expiry date: Mar 8, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F7/1804
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The cycloalkano-pyridines are prepared by reacting corresponding cycloalkano-pyridine-aldehydes with suitable organometallic compounds or Wittig or Grignard reagents or reacting compounds of the cycloalkano-pyridine alcohols type with suitable bromine compounds, and optionally varying the functional groups accordingly. The cycloalkanopyridines are suitable as active compounds in medicaments, in particular in medicaments for the treatment of hypertipoproteinaemia and arteriosclerosis.