Regioselective synthesis of DTPA derivatives
US6207858A · kind A · utility
31Cited by
3References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 3, 1999 |
| Grant date | Mar 27, 2001 |
| Priority date | — |
| Expiry date | Mar 3, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a process for high yield regioselective synthesis of DTPA derivatives that eliminates the need for ion exchange chromotographic separation of intermediates. Moreover, as this process yields a single regioisomer of the chelate, it provides for the regiospecific synthesis of desired chelates useful as radiolabeling agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.