Bacterial fibrin-dependent plasminogen activator
US6210667A · kind A · utility
2Cited by
6References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 15, 1998 |
| Grant date | Apr 3, 2001 |
| Priority date | — |
| Expiry date | Dec 15, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition in a preferred embodiment comprises an isolated bacterial protein that induces fibrin-dependent plasminogen activation, and methods for dissolving blood clots in a subject use such a composition. Embodiments also include a nucleic acid encoding such a bacterial protein, a nucleic acid encoding such a bacterial protein as a fusion to another protein, an expression vector with the nucleic acid, and a host cell transformed with the expression vector.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.