Methods and compositions for the priming of specific cytotoxic T-lymphocyte response
US6210873A · kind A · utility
6Cited by
15References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 2, 1991 |
| Grant date | Apr 3, 2001 |
| Priority date | — |
| Expiry date | Dec 2, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/974
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a novel method for the rapid screening of candidate cytotoxic T lymphocyte- (CTL-) inducing compounds, such as peptides, by the in vivo priming of CTLs with synthetic peptides. The use of compounds so identified for the development of CTL vaccines for the treatment of various infectious disorders, including the treatment of viral diseases such as AIDS, herpes, influenza, and feline or bovine leukemia, is also disclosed, as is the use of this methodology for the preparation of specifically primed CTLs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.