Anticoagulant test
US6210904A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 13, 1998 |
| Grant date | Apr 3, 2001 |
| Priority date | — |
| Expiry date | Oct 13, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/70557
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is a method for diagnosing a patient at risk to thrombocytopenia induced by administration of a GP IIb/IIIa receptor antagonist, which comprises combining PA1 i) a plasma sample of the patient; PA1 ii) detectable monoclonal antibody which recognizes induced binding sites formed on the GP IIb/IIIa receptor following association of a fibrinogen receptor antagonist with the GP IIb/IIIa receptor; and PA1 iii) GP IIb/IIIa receptor:GP IIb/III receptor antagonist complex, and determining association of the detectable monoclonal antibody with the complex in the presence of the plasma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.