Patent · US Expired

Anticoagulant test

US6210904A · kind A · utility

8Cited by
21References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 13, 1998
Grant dateApr 3, 2001
Priority date
Expiry dateOct 13, 2018

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/70557
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present invention is a method for diagnosing a patient at risk to thrombocytopenia induced by administration of a GP IIb/IIIa receptor antagonist, which comprises combining PA1 i) a plasma sample of the patient; PA1 ii) detectable monoclonal antibody which recognizes induced binding sites formed on the GP IIb/IIIa receptor following association of a fibrinogen receptor antagonist with the GP IIb/IIIa receptor; and PA1 iii) GP IIb/IIIa receptor:GP IIb/III receptor antagonist complex, and determining association of the detectable monoclonal antibody with the complex in the presence of the plasma.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.