Protein mixtures to induce therapeutic angiogenesis
US6211157A · kind A · utility
9Cited by
27References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 16, 1998 |
| Grant date | Apr 3, 2001 |
| Priority date | — |
| Expiry date | Oct 16, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An angiogenic factor comprising a mixture of proteins derived from bone. The angiogenic protein mixture is produced by a series of steps that allow the proteins to be kept in solution. The angiogenic mixture of bone proteins is produced by a multi-step process that includes at least one ultrafiltration step, an anion exchange chromatography step, a cation exchange chromatography step and a high performance liquid chromatography (HPLC) purification step.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.