Naphtho-fused lactams promote release of growth hormone
US6211174A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 24, 1998 |
| Grant date | Apr 3, 2001 |
| Priority date | — |
| Expiry date | Sep 24, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D267/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to certain naphtho-fused lactams of the general structural formula: ##STR1## wherein and R.sup.1, R.sup.1a, R.sup.1b, R.sup.2a, R.sup.2b, R.sup.3a, R.sup.4, R.sup.5, R.sup.6, A, L, X, n, p and w are as defined herein. These compounds promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to treat physiological or medical conditions characterized by a deficiency in growth hormone secretion, such as short stature in growth hormone deficient children, and to treat medical conditions which are improved by the anabolic effects of growth hormone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.