Antagonists of gonadotropin releasing hormone

US6211224A · kind A · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Lin Chu · Scotch Plains, US
• Mark Goulet · Westfield, US
• Thomas F. Walsh · Stoneham, US
• Matthew J. Wyvratt · Mountainside, US
• Stephanie L. Witkin · Teaneck, US

Key dates

• Filing date: Oct 26, 1998
• Grant date: Apr 3, 2001
• Expiry date: Oct 26, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D209/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

There are disclosed compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women.