Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US6214331A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Dec 12, 1997 |
| Grant date | Apr 10, 2001 |
| Priority date | — |
| Expiry date | Dec 12, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08J2300/14
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The invention is a process for the preparation of crosslinked water-swellable polymer particles. First, an aqueous polymer solution containing a water-soluble polymer having at least one functional group or charge, is combined with aqueous medium. The aqueous polymer solution is then mixed under moderate agitation with an oil medium and an emulsifier to form an emulsion of droplets of the water-soluble polymer. A crosslinking agent capable of crosslinking the functional groups and/or charges in the water-soluble polymer is then added to the emulsion to form crosslinked water-swellable polymer particles. The invention also includes the particles formed by the process and aqueous dispersions containing the particles which are useful for administering to an individual. The particles of the invention are useful for implantation, soft tissue augmentation, and scaffolding to promote cell growth.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.