Passive immunization against Clostridium difficile disease
US6214341A · kind A · utility
59Cited by
5References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 20, 1998 |
| Grant date | Apr 10, 2001 |
| Priority date | — |
| Expiry date | Oct 20, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides active and passive immunization methods for preventing and treating Clostridium difficile infection, which involve percutaneous administration of C. difficile toxin-neutralizing polyclonal immune globulin, C. difficile toxoids, or combinations thereof. Also provided by the invention are C. difficile toxoids, C. difficile toxin-neutralizing polyclonal immune globulin, and methods of identifying subjects that produce C. difficile toxin-neutralizing polyclonal immune globulin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.