Clearance and inhibition of conformationally altered proteins
US6214366A · kind A · utility
10Cited by
4References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 1, 1999 |
| Grant date | Apr 10, 2001 |
| Priority date | — |
| Expiry date | Jun 1, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S424/16
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention provides a method of arresting, preventing and/or reversing the impairment of central and peripheral nervous system function comprising reducing insoluble protein deposit burden by the administration of branched polycationic compounds and pharmaceutical compositions containing such branched polycationic compounds. The compounds used in the preferred method of the invention are branched dendritic polycations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.