Patent · US Expired

Bone substitution material and a method of its manufacture

US6214368A · kind A · utility

228Cited by
44References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 20, 1996
Grant dateApr 10, 2001
Priority date
Expiry dateMay 20, 2016

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S977/926
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides a novel process for converting a standard inert amorphous calcium phosphate precipitate into highly reactive amorphous solids. The amorphous solids can be used to react with other calcium phosphate solids to form a poorly-crystalline synthetic hydroxyapatite that provides both bioactivity and structural integrity. This novel amorphous material can be reacted with other calcium phosphates at or below 37.degree. C. to form a bone-like material consisting of poorly crystalline hydroxyapatite.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.