Melatonin for the production of a peroral pulsatile form of medication

US6214377A · kind A · utility

Assignee

• Jenapharm GmbH · DE

Inventors

• Michael Dittgen · Apolda, DE
• Sabine Fricke · Jena, DE
• Thomas Graser · Erfurt, DE
• Hermann Osterwald · Glückstadt, DE
• Michael Oettel · Jena, DE
• Theodor Hermann Lippert · Tübingen, DE

Key dates

• Filing date: Dec 5, 1995
• Grant date: Apr 10, 2001
• Expiry date: Dec 5, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/4045
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The use of melatonin for the production of peroral pulsatile forms of medications assures the safeguard of an effective level of the medical substance of melatonin in the blood, and which realize a relatively short invasion phase with a controlled delivery in comparison to conventional forms of medication containing melatonin, and which simultaneously exclude the known side effects. A control of the delivery of the melatonin is effected which is associated with the precise adaptation to the illness episodes or the pain attacks of certain illnesses, which can be treated prophylactically and therapeutically with the active agent melatonin.