Method for detecting biologically active compounds from compound libraries

US6214561A · kind A · utility

Inventors

• Thomas Peters · Erlangen, DE
• Bernd Meyer · Munich, DE

Key dates

• Filing date: Nov 25, 1997
• Grant date: Apr 10, 2001
• Expiry date: Nov 25, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/24
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method for detecting at least one substance (a ligand) present in a compound library using at least one additional substance (a receptor) that binds to the ligand comprises adding to the compound library such a receptor that has substantially higher molecular weight than the ligand to be identified, and performing of such a spectroscopic measurement technique with the mixture, without isolating the receptor-ligand complex, that can detect those dipolar resonance phenomena which occur upon a binding of a receptor to a ligand.