Method and apparatus for preparation of chiral beta amino acids using penicilln G acylase
US6214609A · kind A · utility
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3References
17Claims
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Key dates
| Filing date | May 1, 1998 |
| Grant date | Apr 10, 2001 |
| Priority date | — |
| Expiry date | May 1, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P41/006
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for preparing a chiral beta amino acid or its corresponding esters which comprises contacting a racemic beta amino acid, an acyl donor and Penicillin G acylase enzyme under conditions appropriate to stereoselectively acylate one enantiomer of the racemic beta amino acid to its corresponding N-acylated derivative whereby the opposite enantiomer of the beta amino acid is retained in enantiomerically enriched form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.