Method for evaluating target protein quality from fermenter
US6214975A · kind A · utility
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Key dates
| Filing date | Dec 17, 1999 |
| Grant date | Apr 10, 2001 |
| Priority date | — |
| Expiry date | Dec 17, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/814
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A chemiluminescence-based gel assay may be used as an indicator of fermenter health. The assay is performed using a sample of fermentation medium essentially directly from the fermenter (with no need for complicated purification of the sample before performing the assay). Results from the assay may be correlated with the final product purification yield of a given protein/purification protocol system. This may then be used as a predictor of purification yield before actually performing the purification.
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