Patent · US Expired

Method of manufacture of 1,3-oxathiolane nucleosides

US6215004A · kind A · utility

6Cited by
26References
10Claims
0Family size

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Inventors

Key dates

Filing dateAug 12, 1999
Grant dateApr 10, 2001
Priority date
Expiry dateAug 12, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D411/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include efficient methods for the preparation of the 1,3-oxathiolane ring and subsequent condensation of the 1,3-oxathiolane with a pyrimidine or purine base. Using the processes described herein, the compounds can be provided as isolated enantiomers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.