Process for the preparation of halogenated hydroxydiphenyl compounds

US6215029A · kind A · utility

Assignee

• Ciba Specialty Chemicals Corporation · US

Inventors

• Urs Burckhardt · Zürich, CH
• Armando Di Teodoro · Rheinfelden (Baden), DE
• Werner Hölzl · Eschentzwiller, FR
• Dieter Reinehr · Kandern, DE
• Rudolf Zink · Therwil, CH
• Hanspeter Sauter · Schopfheim, DE
• Uwe Gronde · Rheinfelden (Baden), DE

Key dates

• Filing date: Jun 9, 1999
• Grant date: Apr 10, 2001
• Expiry date: Jun 9, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C67/42
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of halohydroxydiphenyl compounds useful for protecting organic materials and articles from microorganisms, of the formula ##STR1## by acylation of a halogenated benzene compound (first stage), etherification of the acylated compound with a halogenated phenol compound (second stage), oxidation of the etherified compound (third stage) and hydrolysis of the oxidized compound in a fourth stage, according to the following reaction scheme: ##STR2## in which R.sub.1 and R.sub.2 independently of one another are F, Cl or Br; R.sub.3 and R.sub.4 independently of one another are hydrogen; or C.sub.1 -C.sub.4 alkyl; m is 1 to 3; and n is 1 or 2.