Methods and compositions for use in perfusion applications
US6218099A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 3, 1999 |
| Grant date | Apr 17, 2001 |
| Priority date | — |
| Expiry date | Feb 3, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M1/3667
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods and compositions for use in perfusion applications are provided. In the subject methods, a subject or derivative thereof, e.g. isolated organ or tissue, is infused, perfused and/or transfused with at least two fluid compositions. The first fluid composition is a non-naturally occurring biological buffer free plasma-like solution and the second fluid composition is a fluid blood composition. In a preferred embodiment, an additional volume of the first solution, or a derivative thereof, is administered to the patient following introduction of the fluid blood composition. Also provided are kits and systems for performing the subject methods. The subject methods and compositions find use in variety of perfusion applications, including the treatment of hypothermic surgical applications, cryogenic procedures, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.