Compositions and methods for identifying agents that quantitatively alter detectable extramitochondrial DNA:mitochondrial DNA ratios
US6218117A · kind A · utility
16Cited by
2References
36Claims
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Key dates
| Filing date | Jun 15, 1998 |
| Grant date | Apr 17, 2001 |
| Priority date | — |
| Expiry date | Jun 15, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/172
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Compositions and methods based on quantification of extramitochondrial DNA (exmtDNA) sequences are provided that are useful for detecting the presence of or risk for having a disease associated with altered mitochondrial function, and for identifying agents suitable for treating such diseases. The exmtDNA sequences have strong homology to authentic mitochondrial DNA (mtDNA) sequences.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.