Dopamine transporter knockout mice
US6218595A · kind A · utility
4Cited by
1References
16Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 14, 1998 |
| Grant date | Apr 17, 2001 |
| Priority date | — |
| Expiry date | Aug 14, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/0356
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A recombinant rodent comprises cells containing a pair genomic dopamine transporter protein alleles, wherein at least one of said alleles is incapable of expressing endogenous dopamine transporter protein. The rodent may be a homozygote, where both of said alleles are incapable of expressing endogenous dopamine transporter protein, or the rodent may be a heterozygote, and one of said alleles expresses endogenous dopamine transporter protein. The rodent is preferably a mouse.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.