Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues
US6219577A · kind A · utility
535Cited by
45References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 19, 1999 |
| Grant date | Apr 17, 2001 |
| Priority date | — |
| Expiry date | Feb 19, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/306
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Catheter-based devices for enhancing the local delivery of drugs, pharmaceuticals, plasmids, genes, and other agents into the wall tissues of tubular compartments of the living body. One catheter device provides an electrical driving force that can increase the rate of migration of drugs and other therapeutic agents out of a polymer matrix into body tissues and cells using iontophoresis only. Another device uses iontophoresis only, electroporation only, or combined iontophoresis and electroporation. In the latter device, the two procedures may be applied sequentially in any order without removing or repositioning the catheter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.