Glial cell line-derived neurotrophic factor
US6221376A · kind A · utility
11Cited by
13References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 22, 1997 |
| Grant date | Apr 24, 2001 |
| Priority date | — |
| Expiry date | Sep 22, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/839
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel neurotrophic factor referred to as glial cell line-derived neurotrophic factor (GDNF) has been identified. Genes encoding GDNF have been cloned and sequenced. Methods and devices are disclosed for the delivery of GDNF using either an implantable cell which expresses human GDNF or a biocompatible semipermeable membrane containing genetically engineered cells which express and secrete the neurotrophic factor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.