Electron-deficient nitrogen heterocycle-substituted fluorescein dyes
US6221604A · kind A · utility
41Cited by
13References
67Claims
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Key dates
| Filing date | Feb 7, 2000 |
| Grant date | Apr 24, 2001 |
| Priority date | — |
| Expiry date | Feb 7, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/80
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides compositions electron-deficient nitrogen heterocycle-substituted fluorescein dyes and methods in which the dyes are conjugated to substrates and used as detection labels in molecular biology experiments. The electron-deficient nitrogen heterocycles include pyridine, quinoline, pyrazine, and the like. Substrates include polynucleotides, nucleosides, nucleotides, peptides, proteins, carbohydrates, and ligands.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.