Process for producing optically active amino compounds
US6221638A · kind A · utility
32Cited by
4References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 23, 1998 |
| Grant date | Apr 24, 2001 |
| Priority date | — |
| Expiry date | Apr 23, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/83
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The method for preparing an optically active (R)-amino compound characterized by the method comprising stereoselectively carrying out amino group transfer by action of an (R)-form-specific transaminase in the co-presence of a ketone compound (amino acceptor), and an amino compound (amino donor) of a racemic form or an (R)-form, to give an optically active (R)-amino compound. According to the present invention, it is made possible to easily prepare at a high yield the optically active (R)-amino compounds and the like having an aryl group and the like at their 1-position, which have been conventionally difficult to prepare.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.