Patent · US Expired

Blood coagulation protein antagonists and uses therefor

US6221659A · kind A · utility

4Cited by
1References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 16, 1998
Grant dateApr 24, 2001
Priority date
Expiry dateJan 16, 2018

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Coagulation protein antagonists are disclosed, which include monoclonal-type antibodies and related cell lines disclosed for the production of specific, neutralizing antibodies against factors VII and VIIa and the tissue factor/factor VIIa bimolecular complex, which antibodies are useful for the prevention or treatment of thrombotic and related diseases, for immunoaffinity isolation and purification of factors VII and VIIa and the tissue factor/factor VIIa complex, and for determination of factors VII or VIIa and the tissue factor/factors VII or VIIa complex in a biological sample.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.