Antifungal peptides from scleroderma texense

US6221844A · kind A · utility

Assignee

• Aventis Pharma Deutschland GmbH · DE

Inventors

• Heike Stump · Karben, DE
• Wilhelm Stahl · Idstein, DE
• Joachim Wink · Rödermark, DE
• Astrid Markus · Liederbach, DE
• Herbert Kogler · Königstein, DE
• Jurgen Backhaus · Edingen-Neckarhausen, DE

Key dates

• Filing date: May 18, 1999
• Grant date: Apr 24, 2001
• Expiry date: May 18, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to novel peptides, namely texenomycins, from Scleroderma texense, a process for their preparation and their use as pharmaceuticals, in particular as antimycotics. The texenomycins according to the present invention are distinguished in particular by the amino acid sequence I ##STR1## in which PA1 FS is an oxo fatty acid radical, PA1 Aib is aminoisobutyric acid and PA1 Arg-ol=argininol.