DNA methyltransferase genomic sequences and antisense oligonucleotides
US6221849A · kind A · utility
2Cited by
4References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 24, 1998 |
| Grant date | Apr 24, 2001 |
| Priority date | — |
| Expiry date | Jun 24, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/346
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides recombinant nucleic acids comprising nucleic acid sequences from the genomic DNA methyltransferase gene. The invention further provides sequence information for such nucleic acid sequences. In addition, the invention provides antisense oligonucleotides complementary to special regions of the genomic DNA methyltransferase gene or its RNA transcript. Finally, the invention provides methods for using such antisense oligonucleotides as analytical and diagnostic tools, as potentiators of transgenic plant and animal studies and gene therapy approaches, and as potential therapeutic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.