Beta-lactam inhibitors of CoA-IT
US6221860A · kind A · utility
3Cited by
1References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 8, 1999 |
| Grant date | Apr 24, 2001 |
| Priority date | — |
| Expiry date | Nov 8, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/397
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to methods for treating diseases or disorders mediated by lipid inflammatory mediators, arachidonic acid, its metabolites and/or platelet activating factor (PAF), which method comprises administration to a mammal in need thereof of an effective Coenzyme A independent transacylase (CoA-IT) inhibiting amount of a triphenylmethylazetidinone. This invention also relates to a method of treating or reducing inflammation in a mammal in need thereof, which comprises administering to said mammal an effective amount of a triphenylmethylazetidinone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.