8-azabicyclo[3.2.1] octane-3-methanamine derivatives as ligands of D2 and D3 dopamine and 5HT1A and 5HT2 serotonin receptors
US6221879A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 14, 2000 |
| Grant date | Apr 24, 2001 |
| Priority date | — |
| Expiry date | Jul 14, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of general formula (I) ##STR1## in which U represents a group of general formula (A) or (B) ##STR2## in which formulae V represents a hydrogen or halogen atom, a (C.sub.1 -C.sub.3)alkyl group or one or two (C.sub.1 -C.sub.3)alkoxy groups, W and X each represent, respectively, either two oxygen atoms, or an oxygen atom and a CH.sub.2 group, or a CH.sub.2 group and an oxygen atom, or an oxygen atom and a CO group, n represents the number 0 or 1, R represents either a propyl group when U represents a group of general formula (A), or a hydrogen atom or a (C.sub.1 -C.sub.3)alkyl group when U represents a group of general formula (B), Y represents one or more atoms or groups chosen from the following: hydrogen, halogen, (C.sub.1 -C.sub.3)alkyl and (C.sub.1 -C.sub.3)alkoxy, Z represents two hydrogen atoms or an oxygen atom.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.