Amidino derivatives and their use as thrombin inhibitors
US6221898A · kind A · utility
11Cited by
19References
31Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 29, 1997 |
| Grant date | Apr 24, 2001 |
| Priority date | — |
| Expiry date | Aug 29, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/5304
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There is provided compounds of formula I, ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.