Patent · US Expired

Device and method for preventing restenosis

US6223085A · kind A · utility

211Cited by
34References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 6, 1997
Grant dateApr 24, 2001
Priority date
Expiry dateMay 6, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61B2018/1861
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

A method and apparatus for reducing restenosis of a stenotic region of a blood vessel after performing a dilatation angioplasty treatment is disclosed. The method includes radiating microwave energy from a microwave antenna to kill a medial tissue layer of the blood vessel in the stenotic region. The radiation is applied during or after inflation of dilatation balloon to permanently dilate the stenotic region. When radiation is applied during dilatation of the stenotic region, the dilatation balloon forms a seal against the inner wall surface of the blood vessel to exclude blood in the vessel from contacting the stenotic region. The method preferably further includes cooling the blood circulating in the blood vessel about a shaft of the catheter with cooling fluid circulating within cooling lumens of the catheter and cooling an inner wall surface of the blood vessel in the stenotic region during the application of radiation to the medial cell layer. Finally, the method also preferably includes perfusing blood in the vessel through the catheter across the stenotic region during dilatation of the stenotic region to maintain circulation of blood through the blood vessel during the dil…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.