Therapeutic and diagnostic agent delivery
US6224584A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 4, 1999 |
| Grant date | May 1, 2001 |
| Priority date | — |
| Expiry date | May 4, 2019 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2219/00159
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A system for treating a patient's heart which comprises a means to form channels in the heart wall and a means to deliver a therapeutic or diagnostic agent into the channels. Additionally, the system may comprise a means to retain the agent within the channels for a useful period of time. The system may be configured to be introduced percutaneously or intraoperatively. The system generally comprises an elongated, flexible lasing transmission means having a laser radiation emitting means and an delivery lumen opening at the distal end. Practice of the invention comprises forming channels in the heart wall and delivering a therapeutic or diagnostic agent into the channel. Gene therapy agents of this invention comprise vectors for transferring genetic information to the heart tissue in vivo or harvested cells which have been genetically engineered in vitro. Additionally, the invention may comprise retaining the agent within the channels, for example, by incorporating the agent in a viscous carrier.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.