Methods of screening for compounds which mimic galectin-1
US6225071A · kind A · utility
38Cited by
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Key dates
| Filing date | Jul 1, 1999 |
| Grant date | May 1, 2001 |
| Priority date | — |
| Expiry date | Jul 1, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2510/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for treating and modulating an inflammatory response using compositions containing a primarily monomeric or primarily dimeric form of galectin-1. The dimeric form stimulates apoptosis of activated neutrophils while the monomeric form inhibits apoptosis of activated neutrophils. Methods of screening for compounds which have galectin-1-like functions are also identified.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.